DIAZABICYCLOOCTANE DERIVATIVES USEFUL AS .BETA.-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME

Canada Patent

PATENT NO 2874279
APP PUB NO CA-2874279-A1
SERIAL NO

2874279

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Currently available ß-lactamase inhibitors have an inadequate effect against ß-lactamases, which continue to increase constantly. There is a need for novel ß-lactamase inhibitors which can be used in the treatment of bacterial infections caused by resistant bacteria that are currently difficult to treat and that produce: class C ß-lactamase; extended-spectrum ß-lactamase (ESBL) belonging to classes A and D; KPC-2, which decomposes even carbapenem, the last bastion of ß-lactam antibiotics, belonging to class A; and the like. Provided are a compound shown by formula (I), a method for producing the same, a ß-lactamase inhibitor, and a method for treating bacterial infections.

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