INTERLEUKINE 10 IMMUNOCONJUGATES

Canada Patent

APP PUB NO CA-2935665-A1
SERIAL NO

2935665

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Abstract

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The present invention generally relates to fusion proteins of antibodies and interleukin-10 (IL-0). More particularly, the invention concerns fusion proteins of antibodies and mutant IL-10 that exhibit improved properties for use as therapeutic agents, e.g. in the treatment of inflammatory diseases. In addition, the present invention relates to polynucleotides encoding such fusion proteins, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the fusion proteins of the invention, and to methods of using them in the treatment of disease.

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Patent Owner(s)

Patent OwnerAddress
HOFFMANN LA ROCHECHGRENZACHERSTRASSE 124 4070 BASEL CH

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Inventor(s)

Inventor Name Address
MOESSNER EKKEHARD SCHLIEREN
UMANA PABLO C/O ROCHE GLYCART AG WAGISTRASSE 10 8952 SCHLIEREN 8952
EMRICH THOMAS IFFELDORF
HOSSE RALF CHAM
FISCHER JENS 09603 GROSSSCHIRMA
XU DAIGEN 10 TIMBER DRIVE NORTH CALDWELL NEW JERSEY 07006
HANISCH LYDIA JASMIN 8952 SCHLIEREN

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