Novel protein and process for producing same

China Patent

PATENT NO 100448890
APP PUB NO CN-1187824-A
SERIAL NO

96194702

Stats

Importance

Loading Importance Indicators... loading....

Abstract

See full text

A protein having amino acid sequence in SEQ ID No.:1 of the Sequence Listing derived from human MP52, and a dimer protein thereof. A homodimer protein described above can be obtained by constructing a plasmid containing DNA coding amino acid sequence in SEQ ID No.:1 of the Sequence Listing with a methionine at the N-terminus, introducing the plasmid into E. coli for transformation, solubilizing inclusion bodies obtained by culturing the transformant, purifying the monomer protein from the solubilized solution, refolding the monomer protein into a dimer protein and purifying the same. The homodimer protein described above is useful as a pharmaceutical composition for treating cartilage and bone diseases.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
HOECHST MEDICINES AND CHEMICALS CO LTDDEHEIDELBERG GERMANY

International Classification(s)

Inventor(s)

Inventor Name Address
MATSUMOTO TOMOAKI -
SATOH YUSUKE -
ENOMOTO KOICHI -
KIMURA MICHIO NO 30-24 HIGASHIOZONECHO HIGASHI-KU NAGOYA-SHI AICHI-KEN
KATSUURA MIEKO -
FUSAO MAKISHIMA DE
HIDEO MIKI DE
HIROYUKI TAKAMATSU DE
KAWAI NOBUHARU -

Cited Art Landscape

Load Citation