Compositions containing 5-amino-2-hydroxybenzoic acid and a reducing sugar

China Patent

PATENT NO 101010069
APP PUB NO CN-101010069-A
SERIAL NO

200580029172

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Abstract

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Compositions comprising 5-amino-2-hydroxybenzoic acid (5-amino salicylic acid, mesalamine) and a reducing sugar, e.g., lactose, undergo the Maillard and other chemical reactions and produce, in the case of lactose, a degradant 5-[2-Formyl-5-(hydroxymethyl)-1H-pyrrol-1-y]-2-hydroxybenzoic acid. Inventors have developed means to contain and/or reduce the formation of degradants of 5-amino-2-hydroxybenzoic acid.

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Patent Owner(s)

Patent OwnerAddress
PROCTER & GAMBLE LTDUSOHIO USA

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Inventor(s)

Inventor Name Address
WILLIAMS THOMAS D -
KACZANOWSKI MATTHEW J -
REDMAN-FUREY NANCY L -
TROMBLEY KURT F -

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