SPECIFIC ANTAGONIST ANTIBODY FOR THE HETERODIMERO OF ALFA-4-BETA-7

Colombia Patent

APP PUB NO CO-6501170-A2
SERIAL NO

11128767

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Abstract

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The present invention relates to antigen-binding proteins specific for the alpha4beta7 heterodimer, to inhibit cell adhesion to adhesion molecules of MAdCAM-1 vascular cells, said proteins have a heavy chain variable region and a variable region of light chain The present invention also relates to the nucleic acids that encode them, the methods for manufacturing them and pharmaceutical compositions comprising them, for the treatment of various inflammatory conditions.

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Patent Owner(s)

Patent OwnerAddress
AMGEN INCUSONE AMGEN CENTER DRIVE THOUSAND OAKS CALIFORNIA 91320-1799 US

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Inventor(s)

Inventor Name Address
ARORA TARUNA PALO ALTO CA 94306
JACOBSEN FREDERICK W NEWBURY PARK CALIFORNIA 91320
HSU HAILING THOUSAND OAKS CALIFORNIA 91320-1799
FOLTZ IAN BURNABY BRITISH COLUMBIA V5A 4B9

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