Liquid granulocyte colony-stimulating factor formulation, e.g. for treating cancer, neutropenia, HIV infections or neurological disorders, comprises a sugar alcohol, surfactant and acetate buffer

Germany Patent

APP PUB NO DE-102007040932-A1
SERIAL NO

102007040932

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Abstract

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Aqueous liquid formulation of granulocyte colony-stimulating factor (G-CSF) comprises G-CSF, a sugar alcohol, a surfactant (0.04-0.06 mg/ml), an acetate buffer (5-20 mM, pH 4.1-4.4) and optionally amino acids, glyccerol, carbohydrates and/or preservatives. An independent claim is also included for a vessel containing a formulation as above. ACTIVITY : Cytostatic; Immunostimulant; Anti-HIV; Neuroprotective. MECHANISM OF ACTION : Granulocyte colony-stimulating factor.

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Patent Owner(s)

Patent OwnerAddress
BIOGENERIX AGDE68199 MANNHEIM

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Inventor(s)

Inventor Name Address
LUBENAU HEINZ 67435 NEUSTADT AN DER WEINSTRASSE
HINDERER WALTER RODGAU

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