Nucleic Acid Chemical Modifications

European Patent Office Patent

APP PUB NO EP-2669290-A1
SERIAL NO

13004187

Stats

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The present invention provides nucleosides of formula (1) and oligonucleotides comprising at least on nucleoside of formula (2): Another aspect of the invention relates to a method of inhibiting the expression of a gene in cell, the method comprising (a) contacting and oligonucleotide of the invention with the cell; and (b) maintaining the cell from step (a) for a time sufficient to obtain degradation of the mRNA of the target gene.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
ALNYLAM PHARMACEUTICALS INCUSMASSACHUSETTS MASSACHUSETTS

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address
MANOHARAN MUTHIAH CAMBRIDGE MA 02142
RAJEEV KALLANTHOTTATHIL G CAMBRIDGE MA 02142
TAKKELLAPATI SUDHAKAR RAO CAMBRIDGE MA
MATSUDA SHIGEO 140 FIRST STREET SUITE 601 CAMBRIDGE MA 02141 02141
KELIN ALEXANDER V CAMBRIDGE 02142

Cited Art Landscape

Load Citation