THROMBIN SENSITIVE COAGULATION FACTOR X MOLECULES

European Patent Office Patent

APP PUB NO EP-2970933-A2
SERIAL NO

14710844

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Abstract

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The present invention relates to thrombin sensitive coagulation Factor X (FX), as well as use thereof in medicine. In particular the invention relates to FX molecules comprising 2 to 10 amino acid modifications in the activation peptide N-terminally of the FX 'IVGG' motif as well as compositions comprising such molecules and use thereof. Such molecules may be useful in connection with convenient and patient friendly treatment regimens in treatment and prophylaxis of haemophilia.

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Patent Owner(s)

Patent OwnerAddress
NOVO NORDISK ASDKDENMARK BAGSVAERD

International Classification(s)

Inventor(s)

Inventor Name Address
BREINHOLT JENS DYSSEGAARD
BUCHARDT JENS 2880 BAGSVAERD
HANSEN JENS JACOB DK-2880 BAGSVAERD
GANDHI PRAFULL S STORFYRSTINDE OLGAS ALLE 24 DK-2750 BALLERUP DK-2750
ØSTERGAARD HENRIK STORE HAVELSEVEJ 215 DK-3310 ØLSTED DK-3310
WINTHER BALLING KRISTOFFER DK-2880 BAGSVAERD
BLOUSE GRANT E DK-2880 BAGSVAERD

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