ANHYDROUS POLYMORPH A1 OF [(2R,3S,4R,5R)-5-(6-(CYCLOPENTYLAMINO)-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL)] METHYL NITRATE AND PROCESSES OF PREPARATION THEREOF

European Patent Office Patent

APP PUB NO EP-3235825-A1
SERIAL NO

17170990

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Abstract

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The present invention provides a novel anhydrous polymorph form of [(2R,3S,4R,5R) -5-(6-(cyc]opentylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)]methyl nitrate (Compound A). The present invention also provides processes for preparation of the anhydrous polymorphic form of compound A, compositions containing the polymorph form, and use of the polymorph form for the preparation of ophthalmic compositions.

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Patent Owner(s)

Patent OwnerAddress
INOTEK PHARMACEUTICALS CORPUSMASSACHUSETTS

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Inventor(s)

Inventor Name Address
MCVICAR WILLIAM K SUDBURY MA 01776

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