HYDROPHILIC LINKERS FOR ANTIBODY DRUG CONJUGATES

European Patent Office Patent

APP PUB NO EP-3706805-A2
SERIAL NO

18803845

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Abstract

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Described herein protein drug conjugates and compositions thereof that are useful, for example, for the target-specific delivery of drugs to cells. By administering these compounds, compositions, and conjugates as described herein to specific target cells, side-effects due to non-specific binding phenomena, for example, to non-target cells are reduced. In certain embodiments, compounds, compositions, and conjugates are provided, which include hydrophilic residues in linker-payloads and protein conjugates thereof.

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Patent Owner(s)

Patent OwnerAddress
REGENERON PHARMAUS777 OLD SAW MILL RIVER ROAD TARRYTOWN NEW YORK 10591 US

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Inventor(s)

Inventor Name Address
HAN AMY US

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