Compounds and methods of identifying, synthesizing, optimizing and profiling protein modulators

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United States of America Patent

PATENT NO 11692998
APP PUB NO 20210215671A1
SERIAL NO

17144895

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Abstract

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This invention relates to methods of identifying, synthesizing, optimizing and profiling compounds that are inhibitors or activators of proteins, both naturally occurring endogenous proteins as well as certain variant forms of endogenous proteins, and novel methods of identifying such variants. The method accelerates the identification and development of compounds as potential therapeutically effective drugs by simplifying the pharmaceutical discovery and creation process through improvements in hit identification, lead optimization, biological profiling, and rapid elimination of toxic compounds. Implementation results in overall cost reductions in the drug discovery process resulting from the corresponding increases in efficiency.

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Patent Owner(s)

  • HMI MEDICAL INNOVATIONS, LLC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Balash, Monica E Farmington Hills, US 10 1
Housey, Gerard M Southfield, US 32 74

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