HDAC inhibitors, alone or in combination with BTK inhibitors, for treating chronic lymphocytic leukemia

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United States of America Patent

PATENT NO 11813261
APP PUB NO 20190209559A1
SERIAL NO

16093278

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed are histone deacetylase (HDAC) inhibitors, or combinations comprising an HDAC inhibitor and a Bruton's tyrosine kinase (BTK) inhibitor, for the treatment of chronic lymphocytic leukemia in a subject in need thereof. Also provided herein are methods for treating chronic lymphocytic leukemia in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an HDAC inhibitor, or a combination comprising an HDAC inhibitor and a BTK inhibitor. Other related methods are disclosed.

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Patent Owner(s)

  • ACETYLON PHARMACEUTICALS, INC.; H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ibarz, Javier Pinilla Tampa, US 1 3
Jones, Simon S Harvard, US 10 233
Quayle, Steven N Brookline, US 1 3
Sahakian, Eva Tampa, US 2 42

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