N-carbobenzyloxy (N-CBZ)-deprotecting enzyme and uses therefor
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United States of America Patent
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Apr 13, 2010
Grant Date -
Apr 23, 2009
app pub date -
Apr 28, 2008
filing date -
Jan 4, 2001
priority date (Note) -
Expired
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Abstract
This invention relates to isolated or recombinant N-carbobenzyloxy-deprotecting enzyme polypeptides that catalyze the removal of carbobenzyloxy from carbobenzyloxy-protected amino acids and alcohols. Also related are isolated nucleic acids encoding N-carbobenzyloxy-deprotecting enzyme polypeptides thereof, as well as vectors and host cells comprising these nucleic acids. The invention also relates to methods of obtaining isolated nucleic acids, polypeptides, and antibodies, and methods of using the polypeptides in various reactions for industrial or pharmaceutical applications.
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