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Abstract

A sterol derivative represented by the general formulas (I) or (II) which is widely usable as the external base for the skin, emulsifier, etc., for cosmetics, toiletries, medicines, etc., since they have an excellent effect of remedying the chaps of the skin, are capable of stabilizing the lamellar liquid crystal structure and have an excellent surface-activating effect: ##STR1## wherein: R.sup.1 represents a residue remaining after removing the hydrogen atom from the hydroxyl group of a sterol having one hydroxyl group, R.sup.2 represents a group of the formula: ##STR2## (in which R.sup.3 represents an alkenyl or alkyl group having 6 to 20 carbon atoms), M represents a hydrogen atom, alkali metal, etc., and L represents an alkaline earth metal. A dermatologic external preparation having an excellent effect of remedying the chaps of the skin, and being capable of stabilizing the lamellar liquid crystal structure, which comprises a ceramide and/or a structural analog of a ceramide, and the above-described sterol derivative.

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First Claim