Selective ablation of pain-sensing neurons by administration of a vanilloid receptor agonist

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United States of America Patent

PATENT NO 8338457
SERIAL NO

12776304

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Abstract

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The present invention provides methods and kits for the selective ablation of pain-sensing neurons. The methods comprise administration of a vanilloid receptor agonist to a ganglion in an amount that causes death of vanilloid receptor-bearing neurons. Accordingly, the present invention provides methods of controlling pain and inflammatory disorders that involve activation of vanilloid receptor-bearing neurons.

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Patent Owner(s)

  • THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Iadarola, Michael J Washington, US 12 85
Karai, Laszlo Kensington, US 4 12
Olah, Zoltan Kensington, US 11 431

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