Muscular atrophy-inducing agent using hypometabolism-inducing substance T1AM, and use thereof in treating muscular hypertrophy

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United States of America

PATENT NO 11974970
APP PUB NO 20210000767A1
SERIAL NO

17029791

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Abstract

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A muscular atrophy-inducing agent containing, as an active ingredient, a hypometabolism-inducing substance selected from the group consisting of 3-iodothyronamine (T1AM), [D-Ala2,D-Leu5] enkephalin (DADLE), 5′-adenosine monophosphate (5′-AMP), and hydrogen sulfide (H2S), and a method for preventing or treating muscular hypertrophy; and a method for shrinking facial muscle are proposed. The muscular atrophy study model can provide a study model for an economic muscular atrophy study by using a hypometabolism-inducing substance which can be mass-produced, has an effect which may be usefully used by verification for screening of a drug for preventing or treating muscular atrophy, and can be usefully used as a compositions for preventing or treating muscular hypertrophy and a composition for facial muscle shrinkage through the muscular atrophy effect.

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Patent Owner(s)

  • UNIVERSITY INDUSTRY FOUNDATION, YONSEI UNIVERSITY WONJU CAMPUS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Choi, Inho Wonju-si, KR 60 281
Chung, Chan-Moon Yonsei University Gangwon-do, KR 2 28

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