Antibodies for Siglec-15 and methods of use thereof

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United States of America Patent

PATENT NO 11390675
APP PUB NO 20190202912A1
SERIAL NO

16334409

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Abstract

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Siglec-15 binding molecules are provides. The molecules are typically an antibody or antigen binding fragment thereof that immunospecifically binds to Siglec-15. Siglec-15 ligand-binding molecules are also provided. The molecules are typically Siglec-15 polypeptide or fusion protein. Methods of using the molecules to reduce Siglec-15 mediated immunosuppression in a subject in need thereof are also provided.

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Patent Owner(s)

  • NEXTCURE, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Flies, Benjamin Dallas Rockville, US 1 1
Langermann, Solomon Baltimore, US 41 1135
Liu, Linda Clarksville, US 35 1287

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