Generating mammalian T cell activation inducible synthetic promoters (SYN+PRO) to improve T cell therapy

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United States of America Patent

PATENT NO 11851649
SERIAL NO

16613025

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Abstract

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Aspects of the invention described herein relate to methods of making and using inducible promoters for transgene expression. The inducible promoters are derived from the NFAT-RE inducible system and are used to improve or enhance T cell survival and proliferation.

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Patent Owner(s)

  • SEATTLE CHILDREN'S HOSPITAL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jensen, Michael C Bainbridge Island, US 76 642
Wei, Jia Redmond, US 54 695

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