Apparatus for applying thermal energy to a receptacle and detecting an emission signal from the receptacle

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United States of America Patent

PATENT NO 11788128
APP PUB NO 20210017576A1
SERIAL NO

17029930

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Abstract

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An apparatus for performing nucleic acid amplification reactions includes a thermally-conductive receptacle holder with front and back surfaces. The front surface includes a row of receptacle wells, and an outer surface of each well has a frustoconical shape, an inner surface of each well receives a receptacle, and each well has a through-hole extending between the inner and outer surfaces thereof. One or more thermal elements in contact with the back surface of the holder alter a temperature(s) of the holder. The apparatus includes multiple optical fibers, and each optical fiber provides optical communication between one of the wells and an excitation signal source and/or an emission signal detector. A first end of each optical fiber is disposed outside, within, or extends through the through-hole of a corresponding well, and a second end of each optical fiber is in optical communication with the excitation signal source and/or the emission signal detector.

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Patent Owner(s)

  • GEN-PROBE INCORPORATED

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Buse, David San Diego, US 30 633
Combs, David Howard San Diego, US 13 23
Hagen, Norbert D Carlsbad, US 77 293
Moore, Tyler Los Gatos, US 40 308
Moravick, Keith Los Gatos, US 23 361
Opalsky, David San Diego, US 108 1013
Prasad, Anita Los Gatos, US 18 47
Richardson, Bruce Los Gatos, US 85 1123

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