Methods of treatment using anti-GDF15 antibodies

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United States of America Patent

PATENT NO 9725505
SERIAL NO

14863870

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Abstract

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Monoclonal antibodies that bind and inhibit the activity of human GDF15 are disclosed. The antibodies can be used to treat body weight loss, including cachexia, associated with the over-expression of human GDF15.

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Patent Owner(s)

  • AVEO PHARMACEUTICALS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abbott, Sandra Boston, US 7 61
Bai, Ailin Newton, US 32 251
Chen, Ting Acton, US 192 4110
Chiu, Maria I Newton Centre, US 3 26
Gyuris, Jeno Lincoln, US 61 561
Lerner, Lorena Newton Centre, US 25 83
Liu, Qing Acton, US 483 5038
Poling, Laura Boston, US 6 54
Tao, Nianjun Brighton, US 7 55
Weiler, Solly Newton, US 16 195
Weng, Zhigang Brookline, US 14 136
Winston,, Jr William M Marlborough, US 30 248

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