Antibodies targeting a galactan-based O-antigen of K. pneumoniae

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United States of America Patent

PATENT NO 11466074
APP PUB NO 20180066041A1
SERIAL NO

15551813

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Abstract

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The invention provides for an isolated antibody that specifically recognizes a galactan-III epitope of the lipopolysaccharide (LPS) O-antigen structure of Klebsiella pneumoniae, which epitope is incorporated in galactan-III repeating units, wherein the galactan-III repeating unit is a branched galactose homopolymer of Formula (I). The invention further provides for a pharmaceutical or diagnostic preparation comprising said antibody, and a method of producing said antibody.

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Patent Owner(s)

  • X4 PHARMACEUTICALS (AUSTRIA) GMBH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Guachalla, Luis Vienna, AT 11 12
Lukasiewicz, Jolanta Katarzyna Wroclaw, PL 2 2
Nagy, Eszter Vienna, AT 76 333
Nagy, Gábor Sopron, HU 21 17
Szijarto, Valeria Vienna, AT 9 1
Visram, Zehra Vienna, AT 5 4

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