Compositions and methods for the therapy and diagnosis of prostate cancer
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United States of America Patent
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Apr 14, 2009
Grant Date -
N/A
app pub date -
Jun 13, 2000
filing date -
Feb 25, 1997
priority date (Note) -
Expired
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Abstract
Compositions and methods for the therapy and diagnosis of cancer, such as prostate cancer, are disclosed. Compositions may comprise one or more prostate-specific proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a prostate-specific protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as prostate cancer. Diagnostic methods based on detecting a prostate-specific protein, or mRNA encoding such a protein, in a sample are also provided.
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