Slow-release sodium fluoride tablet and method for treatment of osteoporosis
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United States of America Patent
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Feb 27, 1990
Issued Date -
N/A
app pub date -
Oct 22, 1987
filing date -
Aug 11, 1983
priority date (Note) -
Expired
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Abstract
A novel slow-release sodium fluoride preparation and its use. Such slow-release sodium preparation comprises carnauba wax and talc and may be used to provide a safe but effective level of fluoride in serum, optimal for the treatment of osteoporosis. Gastrointestinal side effects are minimized by limiting the amount of fluoride released in the stomach and rheumatic complications are reduced by avoiding toxic levels of fluoride is serum. The amount of fluoride absorbed is nevertheless sufficient to stimulate bone formation and prevent fractures. Thus, the maintenance of serum fluoride as encompassed in this invention, allows for a safe and effective treatment of osteoporosis.
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