Pharmaceutical compositions and methods for fabrication of solid masses comprising polypeptides and/or proteins

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 11304993
APP PUB NO 20190008926A1
SERIAL NO

16112558

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

Embodiments of the invention provide shaped masses comprising one or more drugs such as proteins or polypeptides and methods for forming such shaped masses. One embodiment provides a shaped mass comprising a drug such as a protein or polypeptide having a biological activity in the body of a mammal. The shaped mass is formed by compression of a precursor material comprising the drug wherein an amount of biologically active drug in the mass is a preserved above a minimum level. Drugs which may be incorporated into the shaped mass may include one or more glucose regulating proteins such as insulin, incretins; and immunoglobulins such as TNF-inhibiting antibodies or interleukin neutralizing antibodies. Embodiments of the shaped mass may be incorporated into a tissue penetrating member which is inserted into the intestinal wall allowing for the oral delivery of proteins and peptides which would otherwise be degraded in the intestinal tract.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

  • RANI THERAPEUTICS, LLC

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hashim, Mir Fremont, US 48 1286
Imran, Mir Los Altos Hills, US 266 11601
Korupolu, Radhika Fremont, US 27 376
Morales, Mercedes San Francisco, US 11 208

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
3.5 Year Payment $1600.00 $800.00 $400.00 Oct 19, 2025
7.5 Year Payment $3600.00 $1800.00 $900.00 Oct 19, 2029
11.5 Year Payment $7400.00 $3700.00 $1850.00 Oct 19, 2033
Fee Large entity fee small entity fee micro entity fee
Surcharge - 3.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00