Importance

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Abstract

The metabolism and growth of cells is measured by suspending the cells in a liquid medium capable of forming a gel. The resultant suspension is formed into small droplets which droplets are caused to gel. Samples of the gel microdroplets (GMDs) are treated to alter the metabolism or growth of the cells, and the amount of metabolites, or other cellular products or external reaction products within each GMD is measured. The process can be utilized to determine essentially simultaneously the enumeration or count and the antibiotic susceptibility, or susceptibility to other compounds, factors, biological agents or other cells, of the cells which are representative of a larger sample of said cells.

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First Claim