Chimeric antigen receptors targeting B-cell maturation antigen

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United States of America Patent

PATENT NO 11827889
APP PUB NO 20230030998A1
SERIAL NO

17938535

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Abstract

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The invention provides an isolated and purified nucleic acid sequence encoding a chimeric antigen receptor (CAR) directed against B-cell Maturation Antigen (BCMA). The invention also provides host cells, such as T-cells or natural killer (NK) cells, expressing the CAR and methods for destroying multiple myeloma cells.

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Patent Owner(s)

Patent OwnerAddress
THE U S A AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICESBETHESDA MD 20892-7788

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kochenderfer, James N Bethesda, US 33 318

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