On-probe sample cleanup system and method for MALDI analysis
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United States of America Patent
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Feb 3, 2009
Grant Date -
Jan 1, 2009
app pub date -
May 26, 2006
filing date -
May 26, 2006
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A system and method for cleanup of biological samples from contaminants prior to spectroscopy analysis. The system includes a support configured to hold a sample including a liquid having at least one group of biological molecules with a surface of the support binding the molecules at a surface tension angle to the liquid of less than 180 degrees. The system includes an evaporator configured to evaporate liquid from the support, a solvent applicator configured to apply a solvent for dissolution of the contaminants in the sample, and a solvent removal device configured to remove applied solvent from the sample and thereby at least partially remove the contaminants.
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