CRISPR-Cas12J effector polypeptides and methods of use thereof

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United States of America Patent

PATENT NO 11739309
SERIAL NO

17403245

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Abstract

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The present disclosure provides RNA-guided CRISPR-Cas effector proteins, nucleic acids encoding same, and compositions comprising same. The present disclosure provides ribonucleoprotein complexes comprising: an RNA-guided CRISPR-Cas effector protein of the present disclosure; and a guide RNA. The present disclosure provides methods of modifying a target nucleic acid, using an RNA-guided CRISPR-Cas effector protein of the present disclosure and a guide RNA. The present disclosure provides methods of modulating transcription of a target nucleic acid.

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Patent Owner(s)

  • THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Al-Shayeb, Basem Berkeley, US 16 5
Banfield, Jillian F Berkeley, US 32 130
Doudna, Jennifer A Berkeley, US 215 4069
Pausch, Patrick Berkeley, US 15 5

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