Marker proteins for diagnosing liver disease and method of diagnosing liver disease using the same
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United States of America Patent
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Apr 14, 2009
Grant Date -
Jun 1, 2006
app pub date -
Dec 24, 2003
filing date -
Dec 24, 2002
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Abstract
Using the protein chip technology, biological samples such as sera are subjected to proteome analysis. Thus, a protein which is a human fibrinogen α-E chain decomposition product and has a molecular weight of 5,900, a protein which is an apolipoprotein AII decomposition product and has a molecular weight of 7,800, and a protein which is an apolipoprotein AI decomposition product and has a molecular weight of 28,000, each showing an increase or a decrease with the habit of drinking, are newly found out. By detecting or quantifying these proteins, a liver disease in a subject such as one having a problem of drinking can be diagnosed at the early stage.
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