.alpha.-O-linked glycoconjugates, methods of preparation and uses thereof

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United States of America Patent

PATENT NO 6660714
SERIAL NO

09083776

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Abstract

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The present invention provides novel .alpha.-O-linked glycoconjugates such as .alpha.-O-linked glycopeptides, as well convergent methods for synthesis thereof. The general preparative approach is exemplified by the synthesis of the mucin motif commonly found on epithelial tumor cell surfaces. The present invention further provides compositions and methods of treating cancer using the .alpha.-O-linked glycoconjugates.

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Patent Owner(s)

  • SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Xiao-Tao Newark, DE 27 265
Danishefsky, Samuel J Englewood, NJ 112 1050
Glunz, Peter Wilmington, DE 5 90
Hintermann, Samuel Basel, CH 16 112
Kuduk, Scott Harleysville, PA 41 504
Livingston, Philip O New York, NY 24 283
Ragupathi, Govindaswami New York, NY 22 222
Sames, Dalibor New York, NY 28 187
Schwartz, Jacob B Ann Arbor, MI 2 31
Williams, Lawrence New York, NY 18 229

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