Process for preparing enantiomerically pure imidazo[4,5,1-JK][1,4]-benzodiazepin-2(1H)-thiones

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United States of America Patent

PATENT NO 5599982
SERIAL NO

08413756

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Abstract

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Process for preparing enantiomerically pure imidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-thiones of formula ##STR1## starting from 2,6-dihalo-3-nitrobenzyl derivatives (II) and suitably N-protected 1,2-diaminopropanes (III) ##STR2## Novel enantiomerically pure intermediates of formula (III) and (IV) prepared in the course of the present process.

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Patent Owner(s)

  • JANSSEN PHARMACEUTICA NV

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
De, Knaep Alfons G M Turnhout, BE 3 0
Moens, Luc J R Lille, BE 3 0
Vreysen, Eduard J C Mol, BE 3 0

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