Azacyclic ethynyl derivatives
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United States of America Patent
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May 27, 2008
Grant Date -
Aug 4, 2005
app pub date -
May 6, 2003
filing date -
May 7, 2002
priority date (Note) -
Expired
status (Latency Note)
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Abstract
This invention relates to novel azacyclic ethynyl derivatives, which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters.Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
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