Pyranylphenyl naphthalene lactones as inhibitors of leukotriene biosynthesis
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United States of America Patent
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Jul 13, 1993
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N/A
app pub date -
Oct 26, 1992
filing date -
Feb 28, 1991
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Expired
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Abstract
Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis and allograft rejection and in preventing the formation of atherosclerotic plaques.
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