Hepatitis B virus vectors for gene therapy
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United States of America Patent
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-
Feb 21, 2006
Grant Date -
Dec 6, 2001
app pub date -
Apr 19, 2001
filing date -
Apr 20, 2000
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention relates to novel hepatitis B virus vectors for use in gene therapy which can deliver therapeutic genes to liver cells. The invention also provides methods for the production of novel recombinant hepatitis B viruses. The recombinant viruses produced by this invention can deliver therapeutic genes specifically to liver cells either through in vivo or ex vivo therapy protocols. This vector can be used not only to treat liver diseases but also genetic diseases.
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