Transdermal therapeutic system comprising the active subtance 17-.beta.-Estradiol (Anhydrous)
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United States of America Patent
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Oct 27, 1998
Issued Date -
N/A
app pub date -
May 9, 1997
filing date -
Jul 16, 1992
priority date (Note) -
Expired
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Abstract
A transdermal therapeutic system containing the active substance 17-.beta.-estradiol and optionally further active substances has a laminated structure positioned on a backing layer which is essentially impermeable to active substance and moisture, at least one matrix layer and optionally an adhesive layer. The at least one matrix layer or the adhesive layer contains anhydrous 17-.beta.-estradiol in crystalline form.
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