Formation of N-protected 3,6-bis-(4-aminobutyl)-2,5-diketopiperazine through a cyclic α-N-protected amino ester

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United States of America Patent

PATENT NO 11345668
APP PUB NO 20210107880A1
SERIAL NO

17130729

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Abstract

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A method for the synthesis of N-protected 3,6-aminoalkyl-2,5-diketopiperazines is provided. The method includes obtaining a cyclic α-N protected active amino ester and adding it to a mixture of an amine catalyst in an organic solvent.

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Patent Owner(s)

  • MANNKIND, CORP.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bay, William Elliot Ridgefield, US 10 15
Freeman, John J New Fairfield, US 32 345
Kraft, Kelly Sullivan Poughquag, US 17 304
Phanstiel, Otto Oviedo, US 22 90

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