Nanoparticle-attached enzyme cascades for accelerated multistep biocatalysis

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United States of America Patent

PATENT NO 11512305
APP PUB NO 20180171325A1
SERIAL NO

15840283

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Abstract

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A nanoparticle (for example, quantum dot) serves as a substrate for immobilizing enzymes involved in consecutive reactions as a cascade. This results in a significant increase in the rate of catalysis as well as final product yield compared to non-immobilized enzymes.

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Patent Owner(s)

  • THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ancona, Mario Alexandria, US 20 50
Diaz, Sebastian A Washington, US 2 0
Medintz, Igor L Springfield, US 38 170
Susumu, Kimihiro Alexandria, US 23 61
Vranish, James N Mechanicsville, US 1 0

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