Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders

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United States of America Patent

PATENT NO 5348974
SERIAL NO

08015778

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Abstract

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This invention relates to the use of tocotrienol, gamma-tocotrienol and delta-tocotrienol in reducing hypercholesterolemia, hyperlipidemia and thromboembolic disorders in mammals. The isolation of these tocotrienols from natural sources and their chemical synthesis is disclosed. The present invention also relates to prodrugs and pharmaceutical compositions of gamma-tocotrienol, delta-tocotrienol and tocotrienol and uses thereof.

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Patent Owner(s)

  • BRISTOL-MYERS SQUIBB COMPANY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Parker, Rex Branford, CT 5 68
Pearce, Bradley C East Hampton, CT 21 223
Qureshi, Asaf A Madison, WI 13 430
Wright, John J North Guilford, CT 66 1406

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