Derivatives of 3,3-diphenylpropylamines
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United States of America Patent
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Jun 10, 2008
Grant Date -
Nov 30, 2006
app pub date -
Aug 10, 2005
filing date -
May 12, 1998
priority date (Note) -
In Force
status (Latency Note)
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Abstract
The invention concerns novel derivatives of 3,3-diphenylpropylamines, methods for their preparation, pharmaceutical compositions containing the novel compounds, and the use of the compounds for preparing drugs. More particularly, the invention relates to novel prodrugs of antimuscarinic agents with superior pharmacokinetic properties compared to existing drugs such as oxybutynin and tolterodine, methods for their preparation, pharmaceutical compositions containing them, a method of using said compounds and compositions for the treatment of urinary incontinence, gastrointestinal hyperactivity (irritable bowel syndrome) and other smooth muscle contractile conditions.
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