Genetically modified MSC and therapeutic methods

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United States of America

PATENT NO 11939591
SERIAL NO

17168645

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Abstract

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This disclosure relates to vectors, isolated cells, compositions, and methods for the treatment of critical limb ischemia and associated disorders. One aspect of the disclosure relates to a vector comprising a nucleic acid encoding a 165A isoform VEGF protein and a promoter that regulates expression of the nucleic acid encoding the VEGF.

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Patent Owner(s)

  • THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bauer, Gerhard Davis, US 54 438
Fierro, Fernando Davis, US 6 5
Nolta, Jan Davis, US 8 9
Pepper, Karen Davis, US 6 5

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