Isolation and characterization of a 120 kDa glycoprotein plasma

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United States of America Patent

PATENT NO 5159063
SERIAL NO

07305458

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Abstract

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A substantially pure, single chain plasma protein of approximately 120 kDa having an N-terminal amino acid sequence EKNGIDIYSLTD, and a mixture of protein fragments having vasodilatory activity which fragments are generated by activated Kallikrein cleavage of the 120 kDa protein.

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Patent Owner(s)

  • THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Frank, Michael M Bethesda, MD 7 27
Hammer, Carl H Gaithersburg, MD 5 14
Jacobs, Ruth M Bethesda, MD 1 2

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