Oligonucleotides associated with antibodies

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United States of America Patent

PATENT NO 11661631
APP PUB NO 20200232032A1
SERIAL NO

16747737

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Abstract

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Disclosed herein include systems, methods, compositions, and kits for determining protein expression and gene expression simultaneously and for sample indexing. In some embodiments, an oligonucleotide associated with a cellular component-binding reagent (e.g., an antibody) comprises one or more of a unique molecular label sequence, a primer adapter, antibody-specific barcode sequence, an alignment sequence, and/or a poly(A) sequence. In some embodiments, the oligonucleotide is associated with the cellular component-binding reagent via a linker (e.g., 5AmMC12).

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Patent Owner(s)

  • BECTON, DICKINSON AND COMPANY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chang, Christina San Jose, US 19 233
Ghadiali, James San Jose, US 13 223
Jensen, Devon San Jose, US 5 21
Lai, Janice H San Jose, US 7 42
Lazaruk, Katherine San Jose, US 16 166
Prosen, Dennis E San Jose, US 5 40
Rosenfeld, David San Jose, US 37 382
Shum, Eleen San Jose, US 40 893

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