Recombinant human sialidases, sialidase fusion proteins, and methods of using the same

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United States of America Patent

PATENT NO 11965188
APP PUB NO 20200339968A1
SERIAL NO

16958914

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Abstract

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The invention relates generally to recombinant human sialidases and recombinant sialidase fusion proteins, wherein the sialidase optionally contains one or more mutations compared to wild-type human sialidase, e.g., a substitution, deletion, or addition of at least one amino acid. The invention also provides antibody conjugates including a sialidase and an antibody or a portion thereof. The invention further relates to methods of using the sialidase fusion proteins or antibody conjugates for treating cancer.

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Patent Owner(s)

  • PALLEON PHARMACEUTICALS INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cao, Lizhi Stoneham, US 7 4
Peng, Li Lexington, US 49 260
Xu, Lihui Chestnut Hill, US 17 201

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