P2X4 receptor antagonist

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 11434207
APP PUB NO 20200223806A1
SERIAL NO

16826877

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to a diazepine derivative represented by the following general formula (I) (in the formula, R1 and R2 represent hydrogen atom and the like, or R1 and R2 bind together to form a naphthalene ring and the like together with the benzene ring to which they bind, R3 and R4 represent hydrogen atom and the like, R5 represents hydrogen atom and the like, R6 and R7 represent hydrogen atom and the like, X represents C, CH or N, Y represents N, NH or C(═O), provided that when X is N, Y is not N or NH, and when X is C or CH, Y is not C(═O), Z represents oxygen atom or sulfur atom, A represents benzene ring and the like, B represents NHC(═O) and the like, D represents an atomic bond and the like, E represents an atomic bond and the like, G represents benzene which may be substituted and the like, and m represents an integer of 0 to 5) or a pharmacologically acceptable salt thereof, and a P2X4 receptor antagonist.

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Patent Owner(s)

  • NIPPON CHEMIPHAR CO. LTD.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Imai, Toshiyasu Tokyo, JP 25 99
Inoue, Kazuhide Fukuoka, JP 35 124
Kobayashi, Kunio Saitama, JP 53 489
Saito, Daisuke Tokyo, JP 142 992
Sakuma, Shogo Saitama, JP 33 193
Ushioda, Masatoshi Tokyo, JP 16 101

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