Methods of preparing cell-binding agent-drug conjugates

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United States of America Patent

PATENT NO 11833214
APP PUB NO 20200405874A1
SERIAL NO

16825127

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Abstract

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The present invention provides methods of preparing a cell-binding agent-cytotoxic agent conjugate comprising a cell-binding agent (CysCBA) having one or more unpaired cysteine residues covalently linked to a cytotoxic agent. Also provided are conjugates prepared by the methods described herein and pharmaceutical composition and methods of use thereof.

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Patent Owner(s)

Patent OwnerAddress
IMMUNOGEN INC830 WINTER STREET WALTHAM MA 02451

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hilderbrand, Scott A Swampscott, US 17 66
Milano, Daniel F Reading, US 3 12

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