Coupling electrochemistry to mass spectrometry and high performance liquid chromatography
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United States of America Patent
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Apr 18, 2006
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Sep 17, 2002
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Sep 20, 2001
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Abstract
A hyphenated technique based on the combination of high performance liquid chromatography (HPLC), electrochemical (coulometric) oxidation (EC) and electrospray ionization (ESI)- or atmospheric pressure chemical ionization (APCI)-mass spectrometry (MS), allows access of selected groups of low and medium polarity analytes to ESI- or APCI-mass spectrometry after HPLC by electrochemical treatment of the sample.
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