TRK tyrosine kinase receptor is the physiological receptor for nerve growth factor
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United States of America Patent
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Sep 22, 1998
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N/A
app pub date -
Jun 7, 1995
filing date -
Mar 14, 1991
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Abstract
The present invention relates to a complex comprising nerve growth factor (NGF) and trk-proto-oncogene protein. The present invention also relates to methods for detecting the presence of NGF and trk-proto-oncogene receptor. The present invention further relates to methods that can be used in diagnostics and therapeutics for neurodegenerative diseases such as Alzheimer's and Huntington's by detecting NGF-trk receptor pairs and the phosphorylation of trk protein.
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