Materials and methods for producing endostatin fusion polypeptides in plant cells

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United States of America Patent

PATENT NO 10844392
APP PUB NO 20180179263A1
SERIAL NO

15579690

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Abstract

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This document provides materials and methods for producing endostatin fusion polypeptides having anti-fibrotic activity. For example, provided herein are fusion polypeptides having an IgG Fc domain and a portion of human endostatin that can form high molecular weight multimers, as well as methods for producing such fusion polypeptides in plant cells.

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MUSC FOUNDATION FOR RESEARCH DEVELOPMENT135 CANNON STREET SUITE 101L CHARLESTON SC 29425

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Feghali-Bostwick, Carol Mt Pleasant, US 3 1
McGee, Matthew Vacaville, US 4 27
Padgett, Hal S Vacaville, US 30 133
Ryan, Terence E Eagleville, US 6 7

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