1-Hydroxymethyl-11-deoxy-16-hydroxy-prosten-1-ol-derivatives
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United States of America Patent
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Sep 8, 1981
Issued Date -
N/A
app pub date -
Apr 3, 1980
filing date -
Apr 3, 1980
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Prostaglandin analogs are disclosed that have the .alpha.-chain terminating with the group --CH(OR')OR' wherein R' and R' are the same or different and are hydrogen, C.sub.1 to C.sub.4 alkanoyl or optionally substituted benzoyl, the substituents selected from the group C.sub.1 to C.sub.4 alkyl, C.sub.1 to C.sub.4 alkoxy, halo and trifluoromethyl. These compounds are useful as hypotensive agents, gastric secretory and platelet aggregation enhibitors and bronchodilators.
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