Integrated device with external light source for probing, detecting and analyzing molecules

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 11959853
APP PUB NO 20220099575A1
SERIAL NO

17497835

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Abstract

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System and methods for analyzing single molecules and performing nucleic acid sequencing. An integrated device includes multiple pixels with sample wells configured to receive a sample, which when excited, emits radiation. The integrated device includes at least one waveguide configured to propagate excitation energy to the sample wells from a region of the integrated device configured to couple with an excitation energy source. A pixel may also include at least one element for directing the emission energy towards a sensor within the pixel. The system also includes an instrument that interfaces with the integrated device. The instrument may include an excitation energy source for providing excitation energy to the integrated device by coupling to an excitation energy coupling region of the integrated device. One of multiple markers distinguishable by temporal parameters of the emission energy may label the sample and configuration of the sensor within a pixel may allow for detection of a temporal parameter associated with the marker labeling the sample.

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Patent Owner(s)

  • QUANTUM-SI INCORPORATED

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cipriany, Benjamin Branford, US 41 642
Fife, Keith G Palo Alto, US 215 4155
Ghasemi, Farshid Guilford, US 30 420
Gyarfas, Brett J Aptos, US 27 579
Kabiri, Ali Guilford, US 51 609
Lackey, Jeremy Foster City, US 69 854
Rothberg, Jonathan M Miami Beach, US 554 35427
Schmid, Gerard Guilford, US 92 920
Sickler, Jason W Arlington, US 45 805
West, Lawrence C Las Vegas, US 92 1668

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